Muscle transcriptome adaptations with mild eccentric ergometer exercise
نویسندگان
چکیده
منابع مشابه
Molecular adaptations of neuromuscular disease-associated proteins in response to eccentric exercise in human skeletal muscle.
The molecular events by which eccentric muscle contractions induce muscle damage and remodelling remain largely unknown. We assessed whether eccentric exercise modulates the expression of proteinases (calpains 1, 2 and 3, proteasome, cathepsin B+L), muscle structural proteins (alpha-sarcoglycan and desmin), and the expression of the heat shock proteins Hsp27 and alphaB-crystallin. Vastus latera...
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BACKGROUND Doxorubicin, a widely used anti-tumour drug, is known to cause muscle loss in cancer patients. METHODS Following an acute dose of doxorubicin injection (2.5 mg/kg per body weight), we examined macrophage distribution in rat soleus muscle challenged by eccentric exercise (downhill running). Long-term doxorubicin treatment (one injection every 3 days) on muscle mass and survival were...
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1 Faculty of Medicine and Surgery, University of “Tor Vergata” Rome (Italy). 2 SPO Sport Performance Optimization Lab, CNMSS, Tunis (Tunisia) 3 UR CIAMS – Motor Control and Perception Group, Sport Sciences Department, Université Paris-Sud, Orsay (France). 4 School of Exercise and Sport Science, University of Verona (Italy). 5 Orthopaedic and Sports Medicine Hospital, Doha (Qatar). Authors subm...
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Participation in exercise has been linked with positive results on the cardiovascular system, metabolism, musculature etc. Some of these benefits are linked with reductions in blood pressure, increases in resting energy expenditure, changes in lipid profile, reductions in fat mass, increases in fat free mass etc. (Evans, 1999). There are different types of exercise that someone can participate ...
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Introduction The systems biological analysis of dynamic protein constellations and the determination of proteomewide alterations due to physiological adaptations play an increasing role in modern sports medicine. Several large-scale studies on the effect of physical training in humans and relevant animal models have decisively improved our global understanding of the molecular and cellular mech...
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ژورنال
عنوان ژورنال: Pflügers Archiv - European Journal of Physiology
سال: 2007
ISSN: 0031-6768,1432-2013
DOI: 10.1007/s00424-007-0303-6